I-NICOTINAMIDE
Intshayelelo
I-Niacinamide, ekwaziwa ngokuba yi-nicotinamide, i-vitamin B3 okanye i-vitamin PP, yi-vitamin enyibilikayo emanzini kwaye ikwii-vitamin B. Inxalenye ye-niacinamide kwezi zakhiwo zimbini ze-coenzyme emzimbeni womntu ineempawu zokongeza i-hydrogen ye-Chemicalbook kunye ne-dehydrogenation, edlala indima kwi-oxidation yebhayoloji. Ukuhanjiswa kwe-hydrogen kunokukhuthaza ukuphefumla kwezicubu, inkqubo ye-oxidation yebhayoloji kunye ne-metabolism, ebaluleke kakhulu ekugcineni ukuthembeka kwezicubu eziqhelekileyo, ngakumbi ulusu, indlela yokugaya ukutya kunye nenkqubo yemithambo-luvo. Xa ingenaso isixa, ibangela i-prosthema kuba ukuphefumla kunye ne-metabolism yeeseli kuyachaphazeleka.
Iimpawu zekhemikhali
I-Niacinamide yikristale emhlophe okanye umgubo wekristale omile okwenaliti, ayinavumba okanye inevumba elincinci, kwaye ikrakra kancinci. Ubuninzi be-relative yi-1.4, kwaye iqondo lokunyibilika yi-129-131℃. I-1g yale mveliso iyanyibilika kwi-1mL yamanzi, i-1.5mL ye-ethanol okanye i-10mL ye-glycerine, kwaye ayinyibiliki kwi-ether. Izinzile. Ayina-asidi, i-alkali kunye nobushushu obuphezulu. Izinzile ekukhanyeni nasekufudumaleni emoyeni owomileyo. Xa ifudunyezwa kwizisombululo ze-alkaline okanye ze-asidi, ivelisa i-niacin.
Umsebenzi we-physiological
Amandla okulwa nemibimbi Amandla okulwa nemibimbi e-niacinamide kukuba ingenza i-ChemicalbookATP isebenze, inike amandla kwiiseli ze-keratin, yonyuse ukwenziwa kwe-collagen, kwaye inentsebenziswano entle, engasetyenziswa nezinye izithako zokulwa nemibimbi. Izifundo ezininzi ekhaya nakwamanye amazwe zibonise ukuba i-niacinamide inokunciphisa ngempumelelo ukuvela kwe-immunosuppression yokukhanya kolusu phantsi kokukhanya kwe-ultraviolet.
